On Determination of Molecular Weight Distribution

Rheological Method for Determining Molecular Weight and Molecular Weight Distribution

Determination of the Molecular Weight Distribution of Chondroitin Sulfate B by Sedimentation Equilibrium.

The discovery that purified protein preparations consist of molecules which are monodisperse with respect to molecular weight was originally entirely unexpected (1). Polymerization processes in general are expected to yield products which contain molecules with a wide range of molecular size, and only a template mechanism of synthesis can reasonably be expected to yield size homogeneity. It is ...

Determination of a molecular weight distribution for intermediate degradation products of bovine plasma albumin

Within the last decade several important stud.ies have been made on the large degradation l">I'oclucts of proteins,. However, little ~V'ork has been done on the intermediate degradation procluc·fis., This s·tudy is co11cerned with the chromatographic separo:tion of intermedi~.te fragments from chrymotryptie hydrolysates of bovine plasma albumin and the determination of the molecular weights of ...

The molecular-weight distribution of glycosaminoglycans.

1. A rapid and sensitive method for the accurate estimation of the molecular-weight distribution of keratan sulphate and chondroitin sulphate isolated from adult bovine nasal septum and intervertebral disc is described. The method utilizes gel chromatography of reductively labelled glycosaminoglycan and end-group estimation of number-average molecular weight for each fraction across the peak of...

Determination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugation

Nanoparticles are finding many research and industrial applications, yet their characterization remains a challenge. Their cores are often polydisperse and coated by a stabilizing shell that varies in size and composition. No single technique can characterize both the size distribution and the nature of the shell. Advances in analytical ultracentrifugation allow for the extraction of the sedime...